I wouldnt even think about turning off my tpms!.
Just last week, I was out riding, when suddenly the red triangle started flashing at me and my tpm readout showed my rear tyre pressure reduced to 36psi, and dropping. I stopped and saw that there was a nail in the tyre. The tyre was deflating at a slow enough rate that gave me enough time to reach the nearest garage where I replenished the pressure, which then gave me the ability to get home.
If not for tpm, the only time I would have realised that I had a punctured tyre would have been when it was nearly flat, leaving me stranded by the road and having to be recovered.